Custom Synthesis & Analytical Chemistry

Precision synthesis and analytical support, from intermediate to impurity.

USPJ Scientific provides specialized scientific and analytical solutions designed to support research, development, testing, and quality-focused applications.

01

Custom Synthesis

Multi-step organic synthesis for intermediates and impurities of varying complexity.

02

Rapid Turnaround

Milligram-to-gram scale, with larger batches available on request.

03

Full Characterization

Every compound shipped with structural and purity data attached.

04

Experienced Team

Chemists and analysts with deep synthetic and analytical backgrounds.

What we do

Three disciplines, one integrated workflow.

From the first building block to the final validated method, our synthetic and analytical teams work in step with your program.

01

Route Design → Scale-Up

API Intermediate Synthesis

Custom synthesis of API intermediates from early route scouting through optimized, reproducible production of key building blocks.

  • Multi-step organic synthesis, mg to multi-gram scale
  • Route scouting & synthetic feasibility assessment
  • Purification: crystallization, chromatography, distillation
  • Custom building blocks not commercially available

02

Reference Standards

Impurity Synthesis

Targeted synthesis of process-related impurities, degradation products, and related substances, fully characterized.

  • Known & hypothesized process-related impurities
  • Forced degradation product synthesis
  • Structural elucidation: NMR, MS, IR interpretation
  • High-purity reference standards, mg to gram scale

03

Method to Data

Analytical Testing

Method development, qualification, and routine testing to characterize intermediates, impurities, and related compounds.

  • HPLC / UHPLC, GC-MS, LC-MS/MS
  • NMR, FTIR, UV-Vis structural confirmation
  • Forced degradation & stability-indicating methods
  • ICP-MS elemental analysis, XRPD, DSC/TGA

Instrumentation

Techniques we run
in-house.

A working analytical bench spanning chromatography, spectroscopy, and solid-state characterization.

HPLC / UHPLC

Assay, related substances, purity profiling

GC / GC-MS

Residual solvent & volatile impurity profiling

LC-MS/MS

Impurity identification, trace-level quantitation

NMR

Structural confirmation, purity assessment

FTIR / UV-Vis

Identity testing, functional group confirmation

Karl Fischer

Water content determination

ICP-MS / OES

Elemental & trace metal analysis

XRPD

Crystal form characterization

DSC/TGA

Thermal characterization

 

About

Built to close the gap between "we need this compound" and "we have the data."

"Our scientists bring years of combined experience in organic synthesis, impurity profiling, and analytical characterization across a wide range of chemical scaffolds."

Scientific Depth

In-house expertise in multi-step organic synthesis, route design, and impurity structure elucidation.

Batch records, spectral data, and purity reports for every project.

Confidentiality agreements and secure handling of client materials and information.

From mg-scale research quantities to larger batches as programs progress.

Dedicated project scientists and transparent communication throughout.

Internal Procedures

Governing synthesis, testing, and documentation.

Maintenance and calibration practices for every instrument.

Careful record-keeping for every project, start to finish.

Strong laboratory practices across the team.

Of client materials and information at every stage.

Our Approach

Expertise that supports every stage of your scientific workflow.

From raw material sourcing to final reporting, our internal procedures are designed to make every result traceable and every project defensible.

Who We Work With

Quality, built into every step.

From raw material sourcing to final reporting, our internal procedures are designed to make every result traceable and every project defensible.

01

Generic pharmaceutical developers

02

Innovator & branded pharma research teams

03

Contract research & development

04

Biotech & specialty chemistry companies

05

Academic & research institutions

Common Questions

Have inquiries? Reach out to us!